Issue: 2020, Vol. 25, No. 3-4

S. E. Myasoedova, Е. S. Poltyreva

CADIOVASCULAR RISK FACTORS IN PATIENTS WITH RHEUMATOID ARTHRITIS: INCIDENCE AND MONITORING EFFECTIVENESS

Keywords

rheumatoid arthritis, cardiovascular risk factors.

Abstarct

Objective – to determine the frequency of various traditional cardiovascular risk (CVR) factors in patients with rheumatoid arthritis (RA) and to reveal the effectiveness of their monitoring in practice. Мaterial and methods. 127 patients with trustworthy RA were examined (average age – 61,43 ± 10,74 years). CVR factors were diagnosed with due regard to national recommendations in cardiovascular prophylaxis [2]. Ten-year death risk from cardiovascular diseases was estimated by SCORE scale. Results and discussion. The most part of the patients had some general CVR factors among them the following parameters were found: age (over 55 years in men and over 65 years in women) – 44,9 %, arterial hypertension (АH) – 79,5 %, hypercholesterolemia – 47,2 %, obesity – 39,4 %, frequently in combination with carbohydrate metabolism disorders – 19 % and 2 type diabetes mellitus (DM) – 9,5 %. Cardiovascular diseases of atherosclerotic genesis were detected in 21,7 % patients, sub-clinical atherosclerosis – in 34,6 %, chronic kidney disease (CKD) with glomerular filtration rate less than 60 ml/min/1,73 м² – in 34,6 %. Patients with extremely high risk (21,3 %) and high risk (50,4 %) predominated. AD level for special purpose – lower 140/90 mm mercury column was achieved in 56,3 % of the examined persons. 23,1 % patients with indications for their administration were given statins without the achievement of low density lipoprotein cholesterol levels for special purpose. Conclusion. Combination of several CVR factors in patients with RА determined high risk of cardiovascular diseases and sub-clinical atherosclerosis. CVR factors underestimation, insufficient AH and dyslipidemia monitoring were revealed in patients with RA.

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• Vestnik_3-4_2020-20-25