Issue: 2018, Vol. 23, No. 2

Nilova O. V., Kolbasnikov S. V.

INTERACTION OF EPICARDIUM OBESITY, RISK FACTORS AND TARGET ORGANS LESION IN OLD AND ELDERLY PATIENTS WITH ARTERIAL HYPERTENSION

Keywords

arterial hypertension, risk factors, cardiovascular risk, epicardium fat, hyperlipidemia, hyperuricemia, obesity

Abstarct

Actuality. There are certain difficulties in the diagnosis of cardiovascular risk (CVR) in patients over 65 years. The role of epicardium fat in the total cardiovascular risk is studied insignificantly. Objective - to study the interaction of metabolic risk factors, target organs lesion and epicardium fat tissue (EFT) parameters in patients over 65 years with arterial hypertension (AH). Material and methods. 130 patients with AH (average age - 70,6 ± 0,6 years) were examined, among them 28 ones with excessive body mass, 74 ones - with obesity. The traditional factors of cardiovascular risk and target organs lesion were evaluated; echocardiography with epicardium fat thickness (EF) was performed. Results. The average thickness of EF was amounting to 8,4 ± 0,9 mm. This parameter was trustworthy higher (9,1 ± 0,9 mm) in patients with obesity in comparison with persons with normal body mass (6,5 ± 1,0 mm, p = 0,003). The thickness of EF correlated to total cholesterol level (r = 0,71; p = 0,001), triglycerides (r = 0,59; p = 0,001), glycemia (r = 0,79; p = 0,001) in patients with visceral obesity. EF thickness correlated to systolic AP (r = 0,74; p = 0,001) and diastolic AP (r = - 0,50; p = 0,01) of left ventricle myocardium mass index (r = 0,68; p = 0,001), its sizes and volumes (systolic and diastolic) (r from 0,44 to 0,60, p < 0,05). Conclusion. EF thickness correlated to the presence and manifestation of metabolic risk factors - obesity, dyslipidemia, LVMMI, diastolic dysfunction of left ventricle and it corresponded to the analogous regularities in patients of more young age.

Скачать

• 28-31_Нилова