EFFECT OF MATERNAL ETHANOL INTOXICATION ON HEART, LUNG AND ERYTHROCYTE ARAMETERS IN RAT OFFSPRING

Keywords: alcohol, ethanol, rats, heart, lungs, pregnancy, erythrocytes
Abstarct: The objective is to investigate the heart, lung and erythrocyte system parameters of rat offspring under conditions of maternal ethanol intoxication. Material and Methods. The animals were divided into 2 groups. Infant rats from the first (control) group received clean water with a standard diet. The second group of rats received a 15% ethanol solution with a standard diet during pregnancy. The indices of the erythrocyte system, heart and lung parameters were assessed on the 7th, 14th, 21st, 40th and 60th days of the postnatal period of the development. Results and Discussion. Antenatal alcoholization in postnatal ontogenesis in the offspring of rats resulted in the development of anemia and the destroyed dynamics of heart and lung parameters changes. Conclusion. The discontinuance of ethanol intake had a pronounced positive effect on the studied components of the oxygen transport system. However, its function was not fully restored in the postnatal period.

BULLETIN
of the Ivanovo Medical Academy^{ISSN 1606-8157}