Issue: 2020, Vol. 25, No. 2

I. A. Panova, E. A. Rokotyanskaya, A. S. Panaschatenko, O. V. Tikhomirova

DAILY PROFILE OF ARTERIAL PRESSURE AND VASCULAR ELASTICITY PROPERTIES IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION

Keywords

pregnancy, chronic arterial hypertension, preeclampsia, vascular elastic properties, arterial pressure daily monitoring

Abstarct

Hypertensive disorders in pregnant women including chronic arterial hypertension (CAH) are proved to be the important problems in obstetrics, the cause of severe complications in pregnancy, diseases, invalidism and death of mother and fetus. Objective – to study the peculiarities of daily profile of arterial pressure (AP) and remodeling of vascular wall in pregnant women with CAH. Material and methods. Clinical functional examination of 119 pregnant women (24–41 weeks) with CAH was performed. 39 pregnant women without hypertensive disorders composed control group. 24-hour AP monitoring and vascular elasticity properties were made by pulse wave velocity (PWV) definition. Results and discussion. Pregnant women with CAH in comparison with control group demonstrated trustworthy higher indices of PWV and resiliency modulus of arteries of muscular and elastic types. Peculiarities of AP daily profile in the examined groups were revealed. Pulse AP, time index, space index, AP night decrease degree and variability, were trustworthy higher in women with CAP and associated preeclampsia (AP). ROC-analysis of the results of functional examination allowed to work out the additional diagnostic criteria of preeclampsia association in women with CAP. Conclusions. AP daily monitoring (APDM) and vascular elasticity properties examination enlarge the prognostic possibilities of PE association in pregnant women with CAP.

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• Vestnik 2_2020-23-28