Issue: 2020, Vol. 25, No. 1

Yu. A. Fisiuk, N. V. Kharlamova, T. V. Chasha, T. Z. Gorozhanina, A. V. Budalova

CLINICAL RISK FACTORS FOR THE DEVELOPMENT OF FUNCTIONING HEMODYNAMICALLY SIGNIFICANT ARTERIAL DUCT IN PREMATURED NEWBORNS

Keywords

hemodynamically significant functioning arterial duct, prematured newborns, risk factors.

Abstarct

Actuality – the presence of functioning arterial duct is allowed to stipulate the development of severe morbid states in prematured newborns; it required to find new risk factors of its development including clinical ones. Objective – to reveal clinical risk factors for the development of hemodynamically significant functioning arterial duct in prematured newborns. Material and methods. 76 prematured newborns including 76 infants with hemodynamically significant functioning arterial duct (1st group) were examined at Federal State Budgetary Institution “Ivanovo Research Institute of Maternity&Childhood by V.N.Gorodkov” of the Ministry of Health Care of the Russian Federation. 38 newborns without hemodynamically significant functioning arterial duct were enrolled into the 2nd group (comparison group). Results and discussion. Significantly frequent absence of antenatal prevention of respiratory distress-syndrome, more severe asphyxia in birth act, artificial ventilation of lungs from the first minutes of life within three days, necessity in additional oxygen, respiratory insufficiency with subsequent surfactant therapy and cardiotonic support in the first day of life were found in the first group in contrast to the second one. Conclusion. The peculiarities of neonatal period course in prematured newborns might be considered as clinical risk factors for the development of hemodynamically significant functioning arterial duct.

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• Vestnik_1_2020-20-25