PECULIARITIES OF VEGETATIVE REGULATION IN PATIENTS WITH ARTERIAL HYPERTENSION AND METABOLIC SYNDROME

Keywords: vegetative regulation, arterial hypertension, metabolic syndrome.
Abstarct: Alterations in vegetative regulation in comorbid course of arterial hypertension (AH) in combination with metabolic syndrome (MS) are studied insufficiently. Objective – to study the peculiarities of vegetative regulation in patients with AG of I-III stages in combination with MS. Material and methods. 95 patients with AH (47 men and 48 women, average age – 58,7 ± 6,1 years) were enrolled in the study. Patients were subdivided into two groups: the comparison group – АH (without MС) and the basic one – АH with МС. The analysis of cardiac rhythm variability (CRV) by cardiointervalogram was used in order to evaluate vegetative regulation status. Results and discussion. CRV parameters in patients with AH and MC were statistically lower than in patients with AH without MC. Relative sympatheticotony in combination with parasympathetic insufficiency on the background of reduced heart functional possibilities was registered in patients with MC and AH. These alterations intensified with the AH stage increase and reached the most manifestation in AH of II-III stages on the back ground. Conclusions. МС which proceeded in comorbidity with АH aggravated present vegetative disorders in patients with AH on the background of reduced heart functional possibilities; it pointed to the decrease summary level of regulatory systems activity.

BULLETIN
of the Ivanovo Medical Academy^{ISSN 1606-8157}