Issue: 2019, Vol. 24, No. 1

S. E. Myassoedova, E. S. Poltyreva

DAILY PROFILE OF ARTERIAL PRESSURE IN PATIENTS WITH RHEUMATOID ARTHRITIS

Keywords

rheumatoid arthritis, arterial hypertension, daily monitoring of arterial pressure.

Abstarct

Objective - to determine the peculiarities of daily profile of arterial pressure (AP) in patients with rheumatoid arthritis (RA). Material and methods. 127 patients with trustworthy diagnosed RA(118 women and 9 men, average age-61,4+10,7 years) were examined. The duration of the disease was amounting to 0,5-18 years. 126 patients from 127 ones were administered basic anti-inflammatory therapy, 96 ones - methotrexate. Daily AP monitoring (DAPM) was performed by BPLab system (F*yotr Telegin Ltd). Results and discussion. Arterial hypertension (AH) was revealed in 101 from 127 patients with RA (79,53%), among them 87 ones had AH in anamnesis and were administered antihypertensive therapy, in 14 patients "masked AH" was diagnosed for the first time by DAPM results. The given AH variant was revealed in 35,0% among patients with normal and high normal office AP. From 87 patients who already had AH and were administered antihypertensive therapy, target AP level was detected in 56,4% according to the results of office AP measurement and according to DAPM findings - 16% only. The increased AP indices in daily and/or night hours which were corresponded to I stage of AH were revealed in the most part of patients. Among the patients with AH "non-dippers" and "night-peakers" were frequently found and for them the most manifestation of painful syndrome was characteristic feature in comparison with "dippers". Conclusions. DAPM enlarged the diagnostic possibilities for masked and uncontrolled AH in patients with RA. The correction of the treatment of such patients was administered according to the findings of the examination.

Скачать

• Мясоедова С.Е. 25-29