Issue: 2018, Vol. 23, No. 3

Batrak G. A., Kalaeva O. I.

INSULIN PUMP THERAPY: CLINICAL EFFICACY AND INFLUENCE ON PATIENT’S QUALITY OF LIFE

Keywords

diabetes mellitus, insulin, insulin pump, permanent monitoring of glycemia, quality of life, high-technological aid

Abstarct

Actuality. Nowadays insulin pump therapy with permanent monitoring of glucose level is proved to be the most perspective technique of treatment for patients with diabetes mellitus I type; and it is very important to study the quality of life in patients who used such devices. Objective - to estimate clinical effectiveness of insulin pump therapy and to compare the indices of quality of life in patients before and in 12 months after insulin pump therapy. Materials and methods. 30 patients with diabetes mellitus I type who undergone insulin pump therapy have been observed within one year. At the beginning and 12 months later the following parameters were determined in patients with insulin pump therapy: glycemia level on an empty stomach, glycosalated hemoglobin level, alteration of daily glucose dose, hypoglycemic reactions frequency. Inquest in such patients was performed by modified Diabetes Specific Quality of Life Scale. Results. Decrease of glycemia level on an empty stomach from 10,12 ± 0,42 to 7,6 ± 0,15 mmol/l (p < 0,05), HbA1c - from 11,14 ± 0,14 to 7,34 ± 0,09% (p < 0,05), tendency to the diminishment of hypoglycemic reactions quantity were marked in 12 months after administration of insulin pump therapy. Average daily insulin dose was reduced from 61,84 ± 1,13 to 40,12 ± 1,04 unit/day (p < 0,05). In 12 months from the beginning of insulin pump therapy the parameters of quality of life were significantly improved in comparison with initial level upon all scales of the questionnaire. Conclusions: Insulin pump therapy was proved to be one of the effective methods of treatment in patients with diabetes mellitus I type; it allowed to improve the indices of carbohydrate metabolism (decrease of glycemia variability and HbA1c level, diminishment of hypoglycemic reactions number, reduction of daily insulin dose). Administration of insulin pump therapy was conducive to reach the compensation of diabetes mellitus I type and to improve the quality of life in these patients.

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