Issue: 2024, Vol. 29, No. 1

S. M. Noskov, A. V. Snegiriova, L. S. Shepelyaeva, V. A. Gorokhova, R. M. Nagibin, O. M. Parulya

THE INTERRELATION OF BONE MARROW EDEMA WITH OTHER CLINICAL MANIFESTATIONS IN OSTEOARTHRITIS OF KNEE JOINTS

Keywords: osteoarthritis, bone marrow edema, knee joint
Abstarct: There are numerous studies on the problem of osteoarthritis (OA) but the pathogenetic significance of bone marrow edema (BME) in this disease remains unclear. Objective — to compare the occurrence of BME with other clinical manifestations and MRI–signs of OA; to analyze the differences between patient groups in dependence on BME presence. Material and methods. The study was performed at the Department of Hospital Therapy of Yaroslavl State Medical University. 122 patients with OA of knee joints (KJ) of I–III X-ray stages were examined. An MRIscan of KJ was performed, joint status was examined by visual analogous pain scale and WOMAC index; among laboratory parameters the concentration of hs-C-reactive protein and neutrophil/lymphocyte ratio were estimated. Results and discussion. In 85% cases of BME a clear dependence of BME detection on MRI-parameters which reflected the degeneration and fibrosis in the cartilage, medial meniscus, anterior cruciate ligament, and synovial membrane was revealed.

BULLETIN
of the Ivanovo Medical Academy^{ISSN 1606-8157}