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BULLETIN
of the Ivanovo Medical AcademyISSN 1606-8157

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Issue: 2020, Vol. 25, No. 3-4

N. V. Nikiforova, N. V. Kerimkulova, О. А. Gromova, I. Yu. Torshin, О. Yu. Кisselyova

CLINICAL DIAGNOSTIC SIGNIFICANCE OF MAGNESIUM LEVEL DETERMINATION IN BLOOD SERUM AND ERYTHROCYTES IN PREGNANT WOMEN WITH UNDIFFERENTIATED DYSPLASIA OF CONNECTIVE TISSUE

Keywords
undifferentiated dysplasia of connective tissue, pregnancy, complications, magnesium, serum, erythrocytes.
Abstarct
Objective – to determine magnesium level in blood serum and erythrocytes in pregnant women with undifferentiated dysplasia of connective tissue (NDCT) and to reveal the interrelation of parameters data with gestational complications. Material and methods. The survey was performed in Ivanovo municipal prenatal clinics and maternity homes. 140 pregnant women were examined on the whole: 90 women with NDCT manifestations (basic group) and 50 ones – without NDCT (control group). Magnesium level in blood serum was determined by biochemical automatic analyzer «Konelab» of «ThermoFisherScientific» company, magnesium content in erythrocytes – by color reaction with yellow titan. Results and discussion. NDCT presence in pregnant women was accompanied by lowered magnesium content in erythrocytes; it served as prognostic criterion of retrochorio hematoma appearance at early terms and arterial hypertension, caused by pregnancy without significant proteinuria. Magnesium level decrease in serum of pregnant women of basic group in III trimester lower 0,8 mmole/l was proved to be the risk factor for cerebral ischemia development in newborns.

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