Issue: 2018, Vol. 23, No. 1

Dobrynina M. L., Shulpina E. Yu., Smirnova D. S., Lebedeva A. A.

IMPROVED DIAGNOSIS FOR BENIGN AND MALIGNANT OVARY TUMORS

Keywords

benign and malignant ovary tumors, cancer, ultrasound examination, dopplerography, CA-125 tumor marker, relative malignancy index

Abstarct

Actuality. Therapeutic tactics and volume of forthcoming operative intervention in ovary tumors are determined in dependence on the probable malignant character of the process and it is difficult to ascertain this fact before the operation. Objective is to improve the diagnosis of ovary malignant tumors by using of relative malignancy index. Material and methods. 98 women with ovary tumors were examined. General clinical examination was performed namely ovary ultrasound examination, dopplerography, determination of CA-125 tumor marker level, calculation of relative malignancy index; the latter included quantitative parameters of instrumental examination results. All patients undergone surgical intervention for tumors and the diagnosis was verified upon the results of histological examination.Results. The malignant character of ovary tumors was suspected in 33 of 98 women (and it was confirmed in 15 persons in operative intervention). Relative malignancy index calculation allowed to suspect ovary malignant process in 25 women (it was confirmed in 20 of them). Serious mistakes of diagnosis such as negative predictions in the presence of malignant tum- ors were more often marked in traditional examination (among 65 women with low probability of malignant process only 9 cancer cases were revealed in operative intervention (13.8%) in comparison with relative malignancy index application (among 73 women with low probability of malignant process only 4 cancer cases were revealed (5.5%, p < 0,05).Conclusions. The application of formalized scale (relative malignancy index) increased the accuracy of the diagnosis of malignant tumors before the operation and this fact was allowed to be rather significant for more detailed planning for forthcoming operative interventions in women with ovary tumors.

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