Issue: 2017, Vol. 22, No. 4
Electric physiology criteria for peripheral nerve regeneration in local resonance vibration exposure
- Keywords
- experimental investigation, regeneration of damaged nerve in rats, vibration impact
- Abstarct
- Objective - to study the course peculiarities of denervation-reinnervation processes in neuromotorapparatus of damaged limb in rats under the influence of local resonance vibration. Material and methods. The investigation was performed in 42 white unbred male rats aged 2-3 months, their weight was amounting to 200-300 g. The first group was formed of healthy animals; sciatic nerve intersection and its epineural suture were performed in the second and the third groups. Local vibration resonance affect on the damaged limb (10 minutes daily, from 7th till 17th days after the intervention) was used in postoperative period in animals from the second group in contrast to the 3rd group (control). Needle and stimulation electric neuromyography on the 14, 28, 35, 42, 49 and 56 days after the operation was used in order to estimate the functional status of neuromuscular apparatus of lower limbs. Results. It was determined that spontaneous muscular activity was absent in healthy animals. The same parameter was also absent in the animals from the second and the third groups on the 14th day of the investigation, but in 28 days spontaneous activity potentials were registered; this fact testified to the readiness of muscular fibers for innervation. The registration frequency of spontaneous activity potentials and M-reaction amplitude were higher in the second group in 49 and 56 days of the observation in comparison to the control group. Conclusions. The usage of local vibration impact on the zone of the damaged limb in the postoperative period allowed to hasten the terms of muscle reinnervation in the damaged limb, to increase the rate of impulse conduction upon the damaged nerve and to improve the indices of motor reaction of reinnervated sural muscle.
Писарев