Issue: 2015, Vol. 20, No. 3

Mazur V. V., Kovsar A. V., Savinkova E. A., Orlov Yu. A., Mazur E. S.

THE EFFICACY OF ANTICOAGULANT PREPARATION OF PATIENTS WITH ATRIUM FIBRILLATION TO SINUS RHYTHM RESTORATION IN CLINICAL PRACTICE

Keywords

atrial fibrillation, peresophageal echocardiography, left atrial auricle thrombosis, warfarin, new oral anticoagulants

Abstarct

246 patients with atrium fibrillation which were prepared to sinus rhythm restoration were examined by peresophageal echocardiography; the atrial auricle thrombus was revealed in 37 patients (15%). Adequate antico- agulant therapy was conducted in 184 patients (74,8%); on this therapy background the thrombosis was detected in 9,2% cases. The treatment was proved to be adequate in 66% cases in warfarin administration and in 93,4% cases - in new oral anticoagulants administration (p< 0,001). On the background of adequate therapy atrial throm- bosis was revealed in 11,5% patients which got warfarin and in 5,6% patients which got new oral anticoagulants (p<0,05). “Living” median of the thrombus which was detected in the first examination was amounting to 2 months in the therapy by warfarin and to 1 month in the therapy by new oral anticoagulants (p<0,05).

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