Issue: 2013, Vol. 18, No. 3
The role of pro- and antiangiogenic growth factors in the determination of preeclampsia severity degree
- Keywords
- PlGF, sFlt-1, endogline, angiogenesis, preeclampsia
- Abstarct
- The aim of our study was the determination of the role of growth vascular factors in the estimation of preeclampsia severity degree. 135 pregnants with preeclampsia of various severity degrees and with physiological course of this pregnancy were enrolled in the study. All patients besides the general clinical examination underwent special examination in order to determine pro- and antiangiogenic growth factors in blood serum by IFA technique. Dysbalance of pro- and antiangiogenic growth factors with predomination of agents which laid obstacles to angiogenesis was observed in preeclampsia. In increasing degree of preeclampsia severity the scale of above mentioned alterations became more significant.
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