Issue: 2012, Vol. 17, No. 4

Baranova А. В., Fadeeva О. Ю., Shilyaev Р. Р., Bedina И. В., Kuznetsova Е. Г.

Аngiоtеnsin соnvеrting еnzуmе id gеnе роlуmоrрhism in thе dеvеlорmеnt аnd рrоgrеssiоnоf кidnеу tиbиlоintеrstitiаl disоrdеrs

Keywords

angiotensin converting enzyme, I/D polymorphism, gene, tubulointerstitial disorders of kidneys, oxaluria, dysmetabolic nephropathy, tubulointerstitial nephritis, children

Abstarct

60 children under school age with kidney tubulointerstitial disorders were examined. The association of angiotensin converting enzyme DD genotype with the development of these diseases was determined in children. It was stated that ACE DD genotype was the predisposition factor of oxaluria transformation into dysmetabolic nephropathy and tubulointerstitial nephritis.