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of the Ivanovo Medical AcademyISSN 1606-8157

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Issue: 2012, Vol. 17, No. 2

Medvedeva Т. В., Chizhov P. A., Smirnova M. P., Gurmach M. A.

TOFISOPAM IN THE CORRECTION OF CLINICAL MANIFESTATIONS, VEGETATIVE AND INSOMNIC DISORDERS IN PATIENTS WITH HEART CONNECTIVE TISSUE DYSPLASIA

Keywords
heart connective tissue dysplasia, tofi sopam, vegetative dysfunction, clinical manifestations, asthenia, sleep disorders
Abstarct
In order to study tofi sopam effi cacy in patients with heart connective tissue dysplasia 55 patients were examined by questionnaire and scheme by A.D.Solovyova, questionnaire of point evaluation of sleep subjective characteristics, MFI-20 scale, hospital scale of anxiety and depression, standard vegetative test of the Central Institute of Traumatology and Orthopedics. It was stated that Grandaxin in the dose of 50 mg daily decreased for certain the manifestation of vegetative dysfunction, frequency of heart pain complaints, palpitation, abdominal pains, headaches, vertigo, sense of air defi ciency, signs of general and physical asthenia, anxiety and depression and also normalized the sleep, increased physical activity, ability to work, motivation and general health status.