Issue: 2011, Vol. 16, No. 3

Bogatova И. К., Sotnikova Н. Ю., Vasilieva И. А., Pesikin О. Н.2, Golovkina О. А.

ТНЕ PECULIARIТIES OF IMMUNE STАTUS IN POSTMENOPAUSAL WOMEN WIТH CLIMACTERIC SYNDROME AND FIBROUS-CYSTIC DISEASE OF MAMMARY GLANDS ON THE BACKGROUND OF HORMONE REPLACEMENT THERAPY

Keywords

menopause, climacteric syndrome, hormone replacement therapy, lmmunestatus, fibrous-cystic disease of mammary glands, monocytes

Abstarct

Immune status indices in women with climacteric syndrome and fibrous-cystic disease of mammary glands after hormone replacement therapy with administration of Femoston l/5 and Klimodien were studied. It was stated that the concomitant fibrous-cystic disease of mammary glands irrеsресtivе of climacteric syndrome presence or absence was accompanied by the increased level of monocytes with intracellular IL-6 production. Hormone replacement therapy led to the decrease of the activated monocytes amount. Femoston 1/5 additionally led to the diminishment of the content of peripheral monocytes with intracellular IL-6 production. It allowed to recommend to administer Femoston for the treatment of the climacteric syndrome in these patients.