Issue: 2011, Vol. 16, No. 1

Golubeva Елена Константиновна, Nazarov Сергей Борисович

INFLUENCE OF FEMALE CHRONIC NITRITE INTOXICATION ON ERYTHRON IN EARLY POSTNATAL ONTOGENESIS IN RATS

Keywords

nitrite intoxication, pregnancy, lactation, ontogenesis, erythropoesis, erythrodieresis

Abstarct

Peculiarities of peripheral blood and erythrodieresis of rat posterity which were exposed to chronic nitrite intoxication in pregnancy and lactation were examined. Alterations of adaptive character were revealed. These alterations limited the damaging action of nitrous oxide and its derivatives on erythron. In 5 days age the intensity of erythropoesis and erythrodieresis was increased. In 14 days of life hematocrit increased average age meanings on the background of former intensive erythropoesis. In rats of 21 days age decompensation signs were noted. To 28 days age these signs disappeared. Discocytes percentage was increased in all terms of the examination.