Issue: 2010, Vol. 15, No. 1

Spivak Е.М., Komrakova С.А.

BONE MINERAL DENSITY AND ITS METABOLIC PECULIARITIES IN SYNDROME OF INDIFFERENTIAL DYSPLASIA OF CONNECTIVE TISSUE

Keywords

syndrome of indifferential dysplasia of connective tossue, osteopeny, children

Abstarct

65 children with indifferential dysplasia of connective tissue were examined; its combination with osteopenia was found in 60% of them. Decrease of bone tissue mineral density in this category of patients was accompanied with diminution of osteocalcine serum concentration. This fact reflected the lessening of osteogenesis intensity. Increase of C-terminal telopeptide level was simultaneously fixed in the absence of osteopeny and it testified to the intensification of collagen disintegration concomitant to connective tissue dysplasia.