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of the Ivanovo Medical AcademyISSN 1606-8157

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Issue: 2013, Vol. 18, No. 2

Grozeva Ya. V., Ushakova S. E., Korolyov D. I.

Vegetative status dynamics in elderly and senile patients with stable stenocardia in antiangina therapy of different variants

Keywords
stable angina, elderly and senile age, ivabradine, beta-adrenoblockers, cardiac rhythm variability
Abstarct
Indices of cardiac rhythm variability were studied in elderly and senile patients with stable angina of II– III functional classes. It was demonstrated that adaptation possibilities of these patients’ organism were increased in three months in optimal monitoring of stenocardia by administration of ivabradine or beta-adrenoblockers and ivabradine combination in antiangina therapy. It was stated that beta-adrenoblockers and ivabradine combination was preferable in comparison with monotherapy by beta-adrenoblockers in decrease of the general background of VNS regulation, parasympathetic insufficiency, cardiac rhythm humoral regulation. With due regard to this fact it was recommended to study cardiac rhythm variability in the process of antiangina therapy selection.

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