Issue: 2025, Vol. 30, No. 2

N. F. Kuneshko, Yu. E. Dobrohotova, A. V. Ershov, A. V. Lazarchuk

ANALYSING NEWBORNS’ STATUS IN WOMEN AFTER PRECONCEPTION PERIOD

Keywords

preonception preparation, fetal growth retardation, antiphospholipid syndrome, TORCH infection, neonatal condition

Abstarct

Objectives – to analyse the condition of newborns in women with complicated somatic and obstetric-gynaecological history underwent preconception preparation (PP); to evaluate the efficacy of PP in high-risk patients and in women with normal pregnancy. Material and Methods. The study involved 280 women underwent a course of PP. The patients were divided into the following groups: group I (n = 69) included the women with confirmed antiphospholipid syndrome (APS); group II (n = 71) included the patients with APS and signs of TORCH infection; group III (n = 53) included the women with signs of TORCH infection only; group IV (n = 87) included the patients diagnosed with fetal growth retardation (FGR) in the previous pregnancy. There were healthy women with singleton physiological pregnancies in the control group (n = 112). All participants underwent PP aimed at minimising the impact of somatic disorders on the course of pregnancy, modifying lifestyle, deactivating signs of infection, and correcting haemostasiological disorders. Results and Discussion. The improvement of pregnancy outcomes was observed in the patients underwent PP course. The condition of newborns and their anthropometric parameters corresponded to the parameters of healthy children. Conclusion. PP reduces the risk of adverse outcomes for both the pregnant woman and the foetus. Courses of preparatory measures may be recommended to women with an aggravated somatic and obstetricgynaecological anamnesis.

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