NEW APPROACHES IN THE TREATMENT OF PATIENTS WITH AUTONOMIC POLYNEUROPATHY OF THE HEART AND TYPE 2 DIABETES MELLITUS

Keywords: diabetes mellitus, polyneuropathy, autonomic heart neuropathy, treatment
Abstarct: Optimization of treatment metho by including levocarnitine, enzyme therapy and combined drug based on inosine, nicotinamide, riboflavin and succinic acid in the traditional regimen and assess it by the result analysis of the clinical and instrumental examination. Material and methods. A comprehensive clinical and neurological examination of 134 patients with diabetic polyneuropathy and type 2 diabetes mellitus was performed using general clinical, neurophysiological (electroneuromyography, cardiointervalography) and statistical research methods. Results and discussion. The use of levocarnitine, enzyme therapy and combined drug based on inosine, nicotinamide, riboflavin and succinic aciddifferent pathogenetic mechanisms of action made it possible to reduce the severity of motor and sensory disorders and improve the autonomic balance of the heart, the latter being an important prognostic factor for patients with diabetes mellitus. Conclusion. The use of such medications as levocarnitine, enzyme therapy and combined drug based on inosine, nicotinamide, riboflavin and succinic acid that enhance the metabolic effect, improve microcirculation, neurotransmission processes in the peripheral neuromotor apparatus, vegetative regulation of internal organs, in particular the heart, due to the results of the study was pathogenetically justified.

BULLETIN
of the Ivanovo Medical Academy^{ISSN 1606-8157}