FEATURES OF CLINICAL COURSE OF CHRONIC HEPATITIS C IN ELDERLY PATIENTS

Keywords: chronic hepatitic С, old age
Abstarct: Objective - to reveal clinical and laboratory peculiarities of chronic hepatitis С (CHC) in elderly patients. Material and methods. 112 case histories of the patients with the diagnosis «Chronic hepatitis С (CHС)» aged from 18 to 80 years who were treated in the infectious diseases hospital in Yaroslavl in 2020–2022 were retrospectively analyzed. Results and discussion. Weakness (80,8 %) and heaviness in the right hypochondrium (71,2 %) were reg- istered as the most frequent complaints in elderly patients with CHC. The increased activity of alkaline phosphatase (52,1 %) and gamma-glutamyltranspeptidase (GGTP) (56,2%) was observed in patients over 60 years more frequently. Pronounced signs of liver fibrosis (F3 and F4 by METAVIR scale) were also ob- served three times more often in elderly patients. Viral load indicators in patients over 60 years were approximately twice as high and on average they were 1,28 × 10 7 copies/ml (in patients under 60 years – 6,29 × 10 6 ). Conclusion. The obtained results testified to the fact that CHC in elderly patients differed in clinical and laboratory indicators and it should be taken into account by doctors in their practical work.

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of the Ivanovo Medical Academy^{ISSN 1606-8157}