Issue: 2016, Vol. 21, No. 3
THE INFLUENCE OF ETIOPATHOGENETIC THERAPY ON PROSTATIC HEMODYNAMICS IN PATIENTS WITH CHRONIC BACTERIAL PROSTATITIS
- Keywords
- chronic bacterial prostatitis, antimicrobic chemotherapy, ginseng, endothelial dysfunction, prostatic hemodynamics
- Abstarct
- Objective - to study the influence of complex therapy with using of vitamin-mineral complex with ginseng on prostatic hemodynamics status in patients with chronic bacterial prostatitis aggravation. Material and methods. 60 men with clinical laboratory aggravation of chronic bacterial prostatitis (average age - 37,4 ± 2,9 years). 1 group (n = 30) were cured with levoflaxacin only, 2 group (n = 30) were treated with levofloxacine and vitamin-mineral complex “Gerimax Ginseng” within 30 days. 30 clinically healthy men were enrolled in control group. Transrectal ultrasound dopplerography was used in order to reveal the disorders of prostatic hemodynamics. Results. The decrease of blood flow peak speed in prostatic arteries, the increase of resistance indices in all large collectors of prostatic gland, the diminishment of blood linear speed in veins were detected in patients with chronic bacterial prostatitis aggravation in comparison with healthy men. Maximal blood flow speed in prostatic and capsular arteries was statistically significantly heightened, the indices of resistance in capsular and urethral arteries were decreased, blood flow linear speed in prostatic veins was increased in patients who were administered vitamin-mineral complex with ginseng. But hemodynamic parameters in patients after 30 days course did not reach the parameters of healthy men and this fact required the necessity of more prolonged course of treatment. Conclusions. Monotherapy with fluorinequinolones did not change the parameters of prostatic hemodynamics but its combination with vitamin-mineral complex with ginseng exerted positive influence on prostatic gland blood circulation; and it could improve the penetration of antibiotic into prostate gland tissue.
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