Issue: 2012, Vol. 17, No. 4

Tsublova E. G., Ivanova T. G., Ivanova T. N., Yasnetsov V. V.

PHARMACOLOGICAL PROPERTIES OF SCHIFF BASES FROM ETHOXIAMINOBENZOTIAZOLE DERIVATIVESGROUP

Keywords

schiff bases, ethoxiaminobenzotiazole derivatives, actoprotector and antihypoxic activity

Abstarct

Actoprotector and antihypoxic properties of schiff bases (new ethoxiaminobenzotiazole derivatives) were investigated in the experiments in white mice. EABTI-CIPHER3 substance was revealed among above men- tioned derivatives; it demonstrated actoprotector and antihypoxic properties on the models of physical work ca- pacity under ordinary conditions and in acute hypoxia of various genesis. The magnitude of the effect exerted by it was comparable and in some cases exceeded the same in other medicinal agents.