Issue: 2012, Vol. 17, No. 1

Vasendin Дмитрий Викторович, Michurina Светлана Викторовна, Ishchenko Ирина Юрьевна

STRUCTURAL ALTERATIONS IN TНYМUS IN ACUTE PERIOD AFTER EXPERIМENTAL НYPERTНERМIA EXPOSURE IN RATS

Keywords

thymus, hyperthermia, Vistar line rats, involution

Abstarct

Thymus cellular composition was examined after experimental hyperthermia in rats. It was determined that this exposure resulted in thymus accidental involution formation. The organ involution corresponded to acute posthyperthermic period and it was expressed in the decrease of the organ relative weight, diminishment of relative square of cortical substance and lymphocyte density in all areas particularly in the inner area of the cortical substance. The increase of the destructive processes, the signs of perivascular oedema and cellular elements migration into lymphatic space and capillaries were revealed at tissular level.