Issue: 2011, Vol. 16, No. 1

Kazak М. В., Sukhovey Н. А., Omelianenko М. Г., Tomilova И. К., Plekhanov В. Г., Manzhos А. П.

ENDOTHELIUM FUNCTIONAL STATE AND HEART ISCHEMIC DISEASE COURSE AFTER SURGICAL INTERVENTIONS

Keywords

heart ischemic disease, arterial hypertension, endothelial dysfunction, angioplasty and stenting of coronary arteries

Abstarct

In order to evaluate the infl uence of endothelial dysfunction on the longterm prognosis after surgical interventions (SI) in patients with heart ischemic disease in combination with arterial hypertension the authors examined 74 patients who were operated 5-8 years ago. The content of nitrates, arginine and desquamative endotheliocytes (DE) or nitrites, citrulline and DE in plasma were combined into integral index of endothelial dysfunction. Trustworthy more expressed endothelial dysfunction was revealed in patients with poor prognosis just after SI and in 5-8 years after SI in comparison with such dysfunction in patients with favourable prognosis.