Gerb 74ae417cc05ef25f84b0015d81454434f599579d3ac11b3bfaaa42f8e29a5826

BULLETIN
of the Ivanovo Medical AcademyISSN 1606-8157

Новости

Статистика


Logotip rgp 938b4d8cf58bb50340e3e564842b9c611ee8018249b093a9e8cd19b9d23ccaba

Issue: 2014, Vol. 19, No. 4

Rybachkov V. V., Chetverikova E. N.

Gene polymorphism associated with risk for arterial hypertension and hereditary thrombophilia development in patients with chronic occlusive diseases of lower limbs

Keywords
atherosclerosis, genetic polymorphism, homozygote, heterozygote
Abstarct
The estimation of genetic markers in occlusive diseases of lower limbs’ arteries was made in the study.104 patients with various stages of lower limbs’ chronic ischemia were examined; 18 genes were determined by polymerase chain reaction technique. The analysis of the obtained data allowed to reveal the connection of the studied genes with the onset of occlusive diseases in lower limbs. The genes of nitric oxide synthase 3 NOS3: 786 and NOS: 894 were proved to be the most significant among them.

Скачать